Tubulin Protein by PurSolutions

Tubulin Protein In Biomedical Research

  • highly conserved superfamily of cytoskeletal proteins
  • alpha and beta tubulin heterodimers polymerize into microtubules, a major component of the cytoskeleton
  • nucleation primarily occurs at the centrosome and other microtubule organizing centers (MTOCs)
  • inherent GTPase activity drives microtubule dynamic instability
  • substrate for kinesin and dynein motor proteins important for intracellular transport
  • primary structural component of the mitotic spindle, cilia, and flagella
  • essential for cell morphology, mitosis, meiosis, and other cellular functions
  • tubulin mutations cause tubulinopathy and neuronal disorders

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