Tubulin Protein by PurSolutions

Tubulin Protein In Biomedical Research

highly conserved superfamily of cytoskeletal proteins
alpha and beta tubulin heterodimers polymerize into microtubules, a major component of the cytoskeleton
nucleation primarily occurs at the centrosome and other microtubule organizing centers (MTOCs)
inherent GTPase activity drives microtubule dynamic instability
substrate for kinesin and dynein motor proteins important for intracellular transport
primary structural component of the mitotic spindle, cilia, and flagella
essential for cell morphology, mitosis, meiosis, and other cellular functions
tubulin mutations cause tubulinopathy and neuronal disorders

Customer Satisfaction Rating 4.8 out of 5 stars

“The Cycled Tubulin from PurSolutions is qualitatively as good as the one that we make in the lab. It is usable for live polymerization assay. To our knowledge, no other company managed to achieve this before and we can definitely recommend it!”

Customer Satisfaction Rating 4.8 out of 5 stars

“The (Ultra-Pure Actin) was good, slower polymerization kinetics than the too-fast Cytoskeleton Inc actin even without gel filtration. We'll order it again.”

Customer Satisfaction Rating 4.8 out of 5 stars

“Great solubility and clear labeling”

Cryopreserved

Lyophilized

Alexa Fluor® 488

Alexa Fluor® 594

Alexa Fluor® 647

Cy5

Biotin-XX

Cryopreserved

Cycled Tubulin™

Catalog Number: 032005

Isolated to >99% purity by polymerization cycling and cryopreserved for optimal performance.

Cycled Tubulin™ is isolated by cycling bovine brain homogenate through conditions that promote tubulin polymerization/depolymerization in high salt buffers. The resulting protein is >99% pure and cryopreserved at 20 mg/ml in 80 mM PIPES, 1 mM MgCl2, and 1 mM EGTA (pH 6.8).

Datasheet |

Our Best Seller! The Most Active And Soluble Tubulin Protein On The Market: $150/mg

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Citations

Ross T, et al. Controlling Organization And Forces In Active Matter Through Optically Defined Boundaries. Nature. 2019. Link

Sandate R, et al. An Allosteric Network In Spastin Couples Multiple Activities Required For Microtubule Severing. Nature Structural & Molecular Biology. 2019. Link

Jiang, et al. Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7. Dev Cell. 2019. Link

And more...

Lyophilized

Lyophilized Tubulin

Catalog Number: 142001

Isolated to >99% by selective precipitation and lyophilized for storage at room temperature.

Lyophilized Tubulin is isolated by selective precipitation from bovine brain homogenate. The resulting protein is >99% pure and lyophilized. When reconstituted with ultrapure water to 40 mg/ml, the buffer conditions are 10 mM Sodium Phosphate, 0.5 mM MgCl2, 0.1 mM GTP, and 0.25 M Trehalose (pH 7.0).

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Tubulin Protein Stored And Shipped At Room Temperature: $105/mg

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Citations

Yao XQ, et al. Navigating the Conformational Landscape of G Protein-Coupled Receptor Kinases during Allosteric Activation. J Biol Chem. 2017. Link

And more...

Alexa Fluor® 488

Labeled Tubulin-Alexa Fluor® 488

Catalog Number: 048805

99% pure tubulin protein conjugated with a green fluorescent dye.

Labeled Tubulin-Alexa Fluor® 488 is generated by covalently linking the dye to random tubulin surface lysines in its polymerized form. The final product is cryopreserved at 20 mg/ml in 50 mM K-Glutamate and 0.5 mM MgCl2 (pH=7.0), and is commonly visualized with a FITC filter set with maximum excitation/emission wavelengths of 494/517 nm.

Datasheet |

The Brightest Green Tubulin Protein On The market: $295/0.1 mg

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Citations

Vemu A, et al. Severing Enzymes Amplify Microtubule Arrays through Lattice GTP-Tubulin Incorporation. Science. 2018. Link

Aslam A and Prodan C. Experimentally Measured Phonon Spectrum of Microtubules. J. Phys. D: Appl. Phys. 2019. Link

And more...

Alexa Fluor® 594

Labeled Tubulin-Alexa Fluor® 594

Catalog Number: 059405

99% pure tubulin protein conjugated with a red fluorescent dye.

Labeled Tubulin-Alexa Fluor® 594 is generated by covalently linking the dye to random tubulin surface lysines in its polymerized form. The final product is cryopreserved at 20 mg/ml in 50 mM K-Glutamate and 0.5 mM MgCl2 (pH=7.0), and is commonly visualized with a Texas Red filter set with maximum excitation/emission wavelengths of 590/617 nm.

Datasheet |

The Brightest Red Tubulin Protein On The Market: $295/0.1 mg

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Citations

Aslam A and Prodan C. Experimentally Measured Phonon Spectrum of Microtubules. J. Phys. D: Appl. Phys. 2019. Link

And more...

Alexa Fluor® 647

Labeled Tubulin-Alexa Fluor® 647

Catalog Number: 064705

99% pure tubulin protein conjugated with a far red fluorescent dye.

Labeled Tubulin-Alexa Fluor® 647 is generated by covalently linking the dye to random tubulin surface lysines in its polymerized form. The final product is cryopreserved at 20 mg/ml in 50 mM K-Glutamate and 0.5 mM MgCl2 (pH=7.0), and is commonly visualized with a Cy5 filter set with maximum excitation/emission wavelengths of 651/672 nm.

Datasheet |

The Brightest Far Red Tubulin Protein On The Market: $295/0.1 mg

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Citations

Zehr EA, et al. Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules. Dev. Cell 2019. Link

Ross T, et al. Controlling Organization And Forces In Active Matter Through Optically Defined Boundaries. Nature. 2019. Link

Farhadi L, et al. Active Self-Organization of Actin-Microtubule Composite Self-Propelled Rods. Front Phys. 2018. Link

And more...

Cy5

Labeled Tubulin-Cy5

Catalog Number: 065005

>99% pure tubulin protein conjugated with a far red fluorescent dye.

Labeled Tubulin-Cy5 is generated by covalently linking the dye to random tubulin surface lysines in its polymerized form. The final product is cryopreserved at 20 mg/ml in 50 mM K-Glutamate and 0.5 mM MgCl2 (pH=7.0), and is commonly visualized with a Cy5 filter set with maximum excitation/emission wavelengths of 649/67 nm.

Datasheet |

The Most Photostable Tubulin Protein On The Market: $295/0.1 mg

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Biotin-XX

Labeled Tubulin-Biotin-XX

Catalog Number: 033305

99% pure tubulin protein conjugated with a long-chain biotin derivative.

Labeled Tubulin-Biotin-XX is generated by covalently linking the biomolecule to random tubulin surface lysines in its polymerized form. The final product is cryopreserved at 20 mg/ml in 50 mM K-Glutamate and 0.5 mM MgCl2 (pH=7.0), and demonstrates an affinity toward streptavidin-coated beads and streptavidin-coated coverslips.

Datasheet |

Tubulin Protein With A Strong Affinity For Streptavidin: $295/0.1 mg

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Citations

Geyer EA. Mechanistic Analysis of Microtubule Dynamics and Regulation. UT Southwestern Dissertation. 2018. Link

And more...

Customer Satisfaction Rating 4.8 out of 5

“The (Ultra-Pure Actin) was good, slower polymerization kinetics than the too-fast Cytoskeleton Inc actin even without gel filtration. We'll order it again.”

Customer Satisfaction Rating 4.8 out of 5

“Great solubility and clear labeling”

Customer Satisfaction Rating 4.8 out of 5

“The Cycled Tubulin from PurSolutions is qualitatively as good as the one that we make in the lab. It is usable for live polymerization assay. To our knowledge, no other company managed to achieve this before and we can definitely recommend it!”

Tubulin Protein In Biomedical Research

Customer Satisfaction Rating 4.8 out of 5 stars

Customer Satisfaction Rating 4.8 out of 5 stars

Customer Satisfaction Rating 4.8 out of 5 stars

Cycled Tubulin™

Our Best Seller! The Most Active And Soluble Tubulin Protein On The Market: $150/mg

Citations

Lyophilized Tubulin

Tubulin Protein Stored And Shipped At Room Temperature: $105/mg

Citations

Labeled Tubulin-Alexa Fluor® 488

The Brightest Green Tubulin Protein On The market: $295/0.1 mg

Citations

Labeled Tubulin-Alexa Fluor® 594

The Brightest Red Tubulin Protein On The Market: $295/0.1 mg

Citations

Labeled Tubulin-Alexa Fluor® 647

The Brightest Far Red Tubulin Protein On The Market: $295/0.1 mg

Citations

Labeled Tubulin-Cy5

The Most Photostable Tubulin Protein On The Market: $295/0.1 mg

Labeled Tubulin-Biotin-XX

Tubulin Protein With A Strong Affinity For Streptavidin: $295/0.1 mg

Citations

Customer Satisfaction Rating 4.8 out of 5

Customer Satisfaction Rating 4.8 out of 5

Customer Satisfaction Rating 4.8 out of 5

Some of our Customers

Customers Include:

Tubulin Protein In Biomedical Research

Customer Satisfaction Rating 4.8 out of 5 stars

Customer Satisfaction Rating 4.8 out of 5 stars

Customer Satisfaction Rating 4.8 out of 5 stars

Cycled Tubulin™

Our Best Seller! The Most Active And Soluble Tubulin Protein On The Market: $150/mg

Citations

Customer Satisfaction Rating 4.8 out of 5

Customer Satisfaction Rating 4.8 out of 5

Customer Satisfaction Rating 4.8 out of 5

Some of our Customers

Customers Include:

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