Generation of Highly Selective, Potent, and Covalent G Protein- Coupled Receptor Kinase 5 Inhibitors
Rowlands RA, et al. Generation of Highly Selective, Potent, and Covalent G Protein- Coupled Receptor Kinase 5 Inhibitors. Journal of Medicinal Chemistry. 2020. Link
Metivier M, et al. Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly. Current Biology. 2020. Link
Povedano JM, et al. A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins. Journal of Medicinal Chemistry. 2020. Link
Mani N, Jiang S, and Subramanian R. Differential Regulation of Single Microtubules and Cross-linked Bundles by a Minimal Three-Protein Module. bioRxiv. 2020. Link
Hirst W, et al. Differences in Intrinsic Tubulin Dynamic Properties Contribute to Spindle Length Control in Xenopus Species. Current Biology. 2020. Link
Li G, et al. Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome. Int J Mol Sci. 2020. Link
Ye L, et al. Insights Into Allosteric Control Of Microtubule Dynamics From A Buried β-tubulin Mutation
That Causes Faster Growth And Slower Shrinkage. Protein Science. 2020. Link
Gao L, et al. Nanoparticles Encapsulating Nitrosylated Maytansine To Enhance Radiation Therapy. ACS Nano. 2020. Link
Alfaro-Aco R, et al. Biochemical Reconstitution Of Branching Microtubule Nucleation. eLife. 2020. Link
King MR and Petry S. Phase Separation Of TPX2 Enhances And Spatially Coordinates Microtubule Nucleation. Nat Commun. 2020. Link
Zehr EA, et al. Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules. Dev. Cell 2019. Link
Aslam A and Prodan C. Experimentally Measured Phonon Spectrum of Microtubules. J. Phys. D: Appl. Phys. 2019. Link
Kapoor V, et al. MTrack: Automated Detection, Tracking, and Analysis of Dynamic Microtubules. Scientific Reports. 2019. Link
Ross T, et al. Controlling Organization And Forces In Active Matter Through Optically Defined Boundaries. Nature. 2019. Link
Sandate R, et al. An Allosteric Network In Spastin Couples Multiple Activities Required For Microtubule Severing. Nature Structural & Molecular Biology. 2019. Link
Schimert KI, et al. Intracellular Cargo Transport By Single-Headed Kinesin Motors. PNAS. 2019. Link
Jiang, et al. Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7. Dev Cell. 2019. Link
Geyer EA. Mechanistic Analysis of Microtubule Dynamics and Regulation. UT Southwestern Dissertation. 2018. Link
Farhadi L, et al. Active Self-Organization of Actin-Microtubule Composite Self-Propelled Rods. Front Phys. 2018. Link
Vemu A, et al. Severing Enzymes Amplify Microtubule Arrays through Lattice GTP-Tubulin Incorporation. Science. 2018. Link
Thawani A, et al. XMAP215 Is a Microtubule Nucleation Factor That Functions Synergistically with the γ-Tubulin Ring Complex. Nat Cell Biol. 2018. Link
Reinemann DN, et al. Processive Kinesin-14 HSET Exhibits Directional Flexibility Depending on Motor Traffic. Curr Biol. 2018. Link
Song JG, et al. Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules. J Cell Biol. 2018. Link
Howes SC, et al. Structural and Functional Differences between Porcine Brain and Budding Yeast Microtubules. Cell Cycle. 2018. Link
Reinemann DN, et al. Collective Force Regulation in Anti-parallel Microtubule Gliding by Dimeric Kif15 Kinesin Motors. Curr Biol. 2017. Link.
Alfaro-Aco R, et al. Structural Analysis of the Role of TPX2 in Branching Microtubule Nucleation. J Cell Biol. 2017. Link
Yao XQ, et al. Navigating the Conformational Landscape of G Protein-Coupled Receptor Kinases during Allosteric Activation. J Biol Chem. 2017. Link