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Generation of Highly Selective, Potent, and Covalent G Protein- Coupled Receptor Kinase 5 Inhibitors

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Rowlands RA, et al. Generation of Highly Selective, Potent, and Covalent G Protein- Coupled Receptor Kinase 5 Inhibitors. Journal of Medicinal Chemistry. 2020. Link

Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin

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Metivier M, et al. Drosophila Tubulin-Specific Chaperone E Recruits Tubulin around Chromatin to Promote Mitotic Spindle Assembly. Current Biology. 2020. Link

A Multipronged Approach Establishes Covalent Modification of β-Tubulin

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Povedano JM, et al. A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins. Journal of Medicinal Chemistry. 2020. Link

Differential Regulation of Single Microtubules and Cross-linked Bundles by a Minimal Three-Protein Module

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Mani N, Jiang S, and Subramanian R. Differential Regulation of Single Microtubules and Cross-linked Bundles by a Minimal Three-Protein Module. bioRxiv. 2020. Link

Differences in Intrinsic Tubulin Dynamic Properties

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Hirst W, et al. Differences in Intrinsic Tubulin Dynamic Properties Contribute to Spindle Length Control in Xenopus Species. Current Biology. 2020. Link

Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome

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Li G, et al. Identification and Characterization of the Lactating Mouse Mammary Gland Citrullinome. Int J Mol Sci. 2020. Link

Insights Into Allosteric Control Of Microtubule Dynamics

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Ye L, et al. Insights Into Allosteric Control Of Microtubule Dynamics From A Buried β-tubulin Mutation
That Causes Faster Growth And Slower Shrinkage.
 Protein Science. 2020. Link

Nanoparticles Encapsulating Nitrosylated Maytansine To Enhance Radiation Therapy

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Gao L, et al. Nanoparticles Encapsulating Nitrosylated Maytansine To Enhance Radiation Therapy. ACS Nano. 2020. Link

Biochemical Reconstitution Of Branching Microtubule Nucleation

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Alfaro-Aco R, et al. Biochemical Reconstitution Of Branching Microtubule Nucleation. eLife. 2020. Link

Phase Separation Of TPX2 Enhances And Spatially Coordinates Microtubule Nucleation

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King MR and Petry S. Phase Separation Of TPX2 Enhances And Spatially Coordinates Microtubule Nucleation. Nat Commun. 2020. Link

Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules

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Zehr EA, et al. Katanin Grips the β-Tubulin Tail through an Electropositive Double Spiral to Sever Microtubules. Dev. Cell 2019. Link

Experimentally Measured Phonon Spectrum of Microtubules

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Aslam A and Prodan C. Experimentally Measured Phonon Spectrum of Microtubules. J. Phys. D: Appl. Phys. 2019. Link

Automated Detection, Tracking, and Analysis of Dynamic Microtubules

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Kapoor V, et al. MTrack: Automated Detection, Tracking, and Analysis of Dynamic Microtubules. Scientific Reports. 2019. Link

Controlling Organization And Forces In Active Matter

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Ross T, et al. Controlling Organization And Forces In Active Matter Through Optically Defined Boundaries. Nature. 2019. Link

An Allosteric Network In Spastin Couples Multiple Activities Required For Microtubule Severing

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Sandate R, et al. An Allosteric Network In Spastin Couples Multiple Activities Required For Microtubule Severing. Nature Structural & Molecular Biology. 2019. Link

Intracellular Cargo Transport By Single-Headed Kinesin Motors

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Schimert KI, et al. Intracellular Cargo Transport By Single-Headed Kinesin Motors. PNAS. 2019. Link

Interplay between the Kinesin and Tubulin Mechanochemical Cycles

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Jiang, et al. Interplay between the Kinesin and Tubulin Mechanochemical Cycles Underlies Microtubule Tip Tracking by the Non-motile Ciliary Kinesin Kif7. Dev Cell. 2019. Link

Mechanistic Analysis of Microtubule Dynamics and Regulation

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Geyer EA. Mechanistic Analysis of Microtubule Dynamics and Regulation. UT Southwestern Dissertation. 2018. Link

Active Self-Organization of Actin-Microtubule Composite Self-Propelled Rods

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Farhadi L, et al. Active Self-Organization of Actin-Microtubule Composite Self-Propelled Rods. Front Phys. 2018. Link

Severing Enzymes Amplify Microtubule Arrays through Lattice GTP-Tubulin Incorporation

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Vemu A, et al. Severing Enzymes Amplify Microtubule Arrays through Lattice GTP-Tubulin Incorporation. Science. 2018. Link

XMAP215 Is a Microtubule Nucleation Factor That Functions Synergistically with the γ-Tubulin Ring Complex

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Thawani A, et al. XMAP215 Is a Microtubule Nucleation Factor That Functions Synergistically with the γ-Tubulin Ring Complex. Nat Cell Biol. 2018. Link

Processive Kinesin-14 HSET Exhibits Directional Flexibility

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Reinemann DN, et al. Processive Kinesin-14 HSET Exhibits Directional Flexibility Depending on Motor Traffic. Curr Biol. 2018. Link

Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules

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Song JG, et al. Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules. J Cell Biol. 2018. Link

Structural and Functional Differences between Porcine Brain and Budding Yeast Microtubules

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Howes SC, et al. Structural and Functional Differences between Porcine Brain and Budding Yeast Microtubules. Cell Cycle. 2018. Link

Collective Force Regulation in Anti-parallel Microtubule Gliding

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Reinemann DN, et al. Collective Force Regulation in Anti-parallel Microtubule Gliding by Dimeric Kif15 Kinesin Motors. Curr Biol. 2017. Link.

Structural Analysis of the Role of TPX2 in Branching Microtubule Nucleation

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Alfaro-Aco R, et al. Structural Analysis of the Role of TPX2 in Branching Microtubule Nucleation. J Cell Biol. 2017. Link

Navigating the Conformational Landscape of G Protein-Coupled Receptor Kinases during Allosteric Activation

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Yao XQ, et al. Navigating the Conformational Landscape of G Protein-Coupled Receptor Kinases during Allosteric Activation. J Biol Chem. 2017. Link