May

Spiraling Kinesins, Small Molecule Degraders, and Foldable Actin Networks Featured Kinesin-14 Motors Drive a Right-Handed Helical Motion of Antiparallel Microtubules Around Each Other Mitra et al.  |  Diez Lab  |  Nature Communications Kinesin motor proteins that simultaneously bind two microtubules aid in remodeling cytoskeletal networks by sliding microtubules along one another. Microtubules can slide together …

Journal Club – May 2020 Read More »

Spindle Heterogeneity, Microtubule Search and Capture, and Bulk Actin Waves Must Read Mechanically Distinct Microtubule Arrays Determine the Length and Force Response of the Meiotic Spindle Takagi et al. | Developmental Cell The spindle is a remarkable macromolecular machine comprised of dynamic microtubules and associated factors. Given its critical job in driving chromosome segregation, the …

Journal Club – May 2019 Read More »