June

Featured Articles

Makaros et al. Mol. Cell. 2023
A study by Makaros et al. explores the role of C-terminal degrons in ubiquitin-independent proteasomal degradation. The study suggests that this mechanism may be crucial in coping with aberrant proteins accumulated in response to cellular stress. The conservation of C-degron-mediated degradation from bacteria to humans is also discussed, highlighting its evolutionary significance.

Spindle-F-Actin, Molecular Gearshifts, and Cytoplasmic Softening Must Read Spindle-F-Actin Interactions in Mitotic Spindles in an Intact Vertebrate Epithelium Kita et al. | Molecular Biology of the Cell A compelling subject for striking microscopy images, microtubules have long been considered the major mechanical component of the mitotic spindle. But a long-standing question has been whether a …

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