Actin Product
Actin Protein In Biomedical Research
- highly conserved superfamily of cytoskeletal proteins
- actin monomers (globular G-actin) polymerize into actin filaments (filamentous F-actin), a major component of the cytoskeleton
- linear and branched nucleation is mediated by formins and the Arp2/3 complex, respectively
- inherent ATPase activity drives actin treadmilling
- substrate for myosin motor proteins
- essential for cardiac, skeletal, and smooth muscle structure and contraction
- associated with cadherins and integrins important for cell adhesion
- function in essential cellular processes including cell migration and cytokinesis
- actin-binding proteins include villin, profilin, cofilin, troponin, tropomyosin, and more
- actin mutations can cause myopathy and other human pathology
- actin inhibitors include toxins such as latrunculin, Cytochalasin D, and phalloidin
Ultra-Pure Actin
Ultra-Pure Actin (>99%)
Catalog Number: 160101
Ultra-Pure Actin is extracted from rabbit skeletal muscle and lyophilized. The resulting product is >99% pure and >90% polymerization competent. When reconstituted with ultrapure water to 3 mg/ml, the buffer conditions are 2 mM Tris-HCl, 0.2 mM CaCl2, 0.2 mM ATP, 1 mM DTT, and 0.25 M Trehalose (pH 8.0).
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Greater Purity at a Better Price: $110/mg
Pure Actin
Pure Actin (>90%)
Catalog Number: 190101
Pure Actin is extracted from rabbit skeletal muscle and lyophilized. The resulting product is >90% pure and >80% polymerization competent. Possible contaminants include a-actinin. When reconstituted with ultrapure water to 9 mg/ml, the buffer conditions are 2 mM Tris-HCl, 0.2 mM CaCl2, 0.2 mM ATP, 1 mM DTT, and 0.25 M Trehalose (pH 8.0).
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Compare to Sigma Aldrich A2522: $65 /mg
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