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Actin Protein In Biomedical Research
- highly conserved superfamily of cytoskeletal proteins
- actin monomers (globular G-actin) polymerize into actin filaments (filamentous F-actin), a major component of the cytoskeleton
- linear and branched nucleation is mediated by formins and the Arp2/3 complex, respectively
- inherent ATPase activity drives actin treadmilling
- substrate for myosin motor proteins
- essential for cardiac, skeletal, and smooth muscle structure and contraction
- associated with cadherins and integrins important for cell adhesion
- function in essential cellular processes including cell migration and cytokinesis
- actin-binding proteins include villin, profilin, cofilin, troponin, tropomyosin, and more
- actin mutations can cause myopathy and other human pathology
- actin inhibitors include toxins such as latrunculin, Cytochalasin D, and phalloidin
Ultra-Pure Actin
Pure Actin
Ultra-Pure Actin
Ultra-Pure Actin (>99%)
Ultra-Pure Actin is extracted from rabbit skeletal muscle and lyophilized. The resulting product is >99% pure and >90% polymerization competent. When reconstituted with ultrapure water to 3 mg/ml, the buffer conditions are 2 mM Tris-HCl, 0.2 mM CaCl2, 0.2 mM ATP, 1 mM DTT, and 0.25 M Trehalose (pH 8.0).
Greater Purity at a Better Price: $110.00/mg
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Pure Actin
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Customer Satisfaction Rating 4.8 out of 5
“The (Ultra-Pure Actin) was good, slower polymerization kinetics than the too-fast Cytoskeleton Inc actin even without gel filtration. We'll order it again.”
Customer Satisfaction Rating 4.8 out of 5
“Great solubility and clear labeling”
Customer Satisfaction Rating 4.8 out of 5
“The Cycled Tubulin from PurSolutions is qualitatively as good as the one that we make in the lab. It is usable for live polymerization assay. To our knowledge, no other company managed to achieve this before and we can definitely recommend it!”
Customers Include:
Customer Satisfaction Rating 4.8 out of 5 stars
"The (Ultra-Pure Actin) was good, slower polymerization kinetics than the too-fast Cytoskeleton Inc actin even without gel filtration. We'll order it again.”
Customer Satisfaction Rating 4.8 out of 5 stars
“Great solubility and clear labeling”
Customer Satisfaction Rating 4.8 out of 5 stars
“The Cycled Tubulin from PurSolutions is qualitatively as good as the one that we make in the lab. It is usable for live polymerization assay. To our knowledge, no other company managed to achieve this before and we can definitely recommend it!”
Customers Include: